Save
Pathologic evidence for disease heterogeneity
ECTRIMS Online Library. Brück W. Oct 12, 2018; 232043
Prof. Wolfgang Brück
Prof. Wolfgang Brück
Login now to access Regular content available to all registered users.

You may also access this content "anytime, anywhere" with the Free MULTILEARNING App for iOS and Android
Abstract
Discussion Forum (0)
Rate & Comment (0)

Abstract: 290

Type: Scientific Session

Abstract Category: N/A

Multiple sclerosis (MS) belongs to the spectrum of inflammatory demyelinating disorders of the central nervous system including classic MS, acute disseminated encephalomyelitis (ADEM), neuromyelitis optica spectrum disorders (NMOSD) and anti-MOG antibody associated demyelination.
The present lecture summarizes the characteristics of the different disease entities mentioned above and their pathological commonalities and differences. MS reveals extensive white and grey matter demyelination as well as involvement of the noral appearing brain tissue. NMOSD is a primary astrocyte disorder with secondary demyelination. Anti-MOG antibody associated demyelination is heterogeneous and shows features of ADEM-like perivascular demyelination and confluent MS-like demyelination.
In summary, the major pathological differences between the different inflammatory demyelinating disease entities in different disease stages are described in detail.
Disclosure: Wolfgang Brück has received honoraria for lectures by Bayer Vital, Biogen, Merck Serono, Teva, Genzyme, Roche and Novartis. He is a member of scientific advisory boards for Teva, Biogen, Novartis, MedDay, Celgene and Genzyme. Wolfgang Brück receives research support from Teva, Biogen, Genzyme, MedDay and Novartis.

Code of conduct/disclaimer available in General Terms & Conditions
Anonymous User Privacy Preferences

Strictly Necessary Cookies (Always Active)

MULTILEARNING platforms and tools hereinafter referred as “MLG SOFTWARE” are provided to you as pure educational platforms/services requiring cookies to operate. In the case of the MLG SOFTWARE, cookies are essential for the Platform to function properly for the provision of education. If these cookies are disabled, a large subset of the functionality provided by the Platform will either be unavailable or cease to work as expected. The MLG SOFTWARE do not capture non-essential activities such as menu items and listings you click on or pages viewed.


Performance Cookies

Performance cookies are used to analyse how visitors use a website in order to provide a better user experience.



Google Analytics is used for user behavior tracking/reporting. Google Analytics works in parallel and independently from MLG’s features. Google Analytics relies on cookies and these cookies can be used by Google to track users across different platforms/services.


Save Settings