The impact of pain and lower limb spasticity to functionality and quality of life in patients with progressive forms of multiple sclerosis
ECTRIMS Online Library. Rodic S. 09/13/19; 278320; P1118
Sindi Rodic
Sindi Rodic
Contributions
Abstract

Abstract: P1118

Type: Poster Sessions

Abstract Category: Clinical aspects of MS - Progressive MS

S. Rodic1, A. Vidakovic1, S. Dedijer Dujovic2, T. Dimkić Tomić2, L. Konstantinovic3

1Neororehabilitation, Clinic for Rehabilitation Dr Miroslav Zotovic, Faculty of Medicine, University of Belgrade, 2Neororehabilitation, Clinic for Rehabilitation Dr Miroslav Zotovic, 3Neororehabilitation, Faculty of Medicine, University of Belgrade, Clinic for Rehabilitation Dr Miroslav Zotovic, Belgrade, Serbia

Introduction: Spasticity is prevalent symptom in multiple sclerosis (MS) with the interrelation between disability and quality of life as the disease progress. Pain, as commonly associated symptom with muscle stiffnes, has significant negative impact on function among people with progressive forms of MS. However, there is variablity of information regarding the impact of pain associated with lower limb spasticity on functionality and quality of life among individuals with diagnosed progressive forms of MS.
Objectives and aims: To correlate the impact of pain and lower limb spasticity to functionality and quality of life in patients with progressive forms of MS.
Methods: Cross-sectional analysis of data from 85 patients with diagnosed primary and secondary progressive MS, The Expanded Disability Status Scale (EDSS) score 2-6.5 and lower limb spasticity were conducted. Patients were reffered to inpatient rehabilitation at Clinic for rehabilitation Dr Miroslav Zotovic in Belgrade. The Modified Ashwort Scale (MAS) was used for the spasticity estimation. The Timed 25 Foot walk (T25FW) was used to quantify the mobility and function of the leg. For correlate functional activity according to pain intensity self-assesment scales: The Multiple Sclerosis Spasticity Scale 88 (MSSS-88) with its subscale Pain and discomfort (PD) and Physical Health Composite Score (PHC) as a part of the Multiple Sclerosis Quality of Life-54 (MSQoL-54) in comparation with Pain domen of the same scale were used.
Results: A statistically significant correlation was found between EDSS and T25 W (rs=0,651; p< 0,001), MAS and EDSS (rs=0,413; p< 0,001), PD subscale and MSSS-88 (r=0,918; p< 0,001), Pain and PHC (r=0,819; p< 0,001). The associations between pain intensity and measures of function are consistent with the literature on the MS population at large.
Conclusions: The results suggest that pain becomes worse in individuals with higher disability score and spasticity level has negative impact on functionality and quality of life.
Disclosure: Nothing to disclose

Abstract: P1118

Type: Poster Sessions

Abstract Category: Clinical aspects of MS - Progressive MS

S. Rodic1, A. Vidakovic1, S. Dedijer Dujovic2, T. Dimkić Tomić2, L. Konstantinovic3

1Neororehabilitation, Clinic for Rehabilitation Dr Miroslav Zotovic, Faculty of Medicine, University of Belgrade, 2Neororehabilitation, Clinic for Rehabilitation Dr Miroslav Zotovic, 3Neororehabilitation, Faculty of Medicine, University of Belgrade, Clinic for Rehabilitation Dr Miroslav Zotovic, Belgrade, Serbia

Introduction: Spasticity is prevalent symptom in multiple sclerosis (MS) with the interrelation between disability and quality of life as the disease progress. Pain, as commonly associated symptom with muscle stiffnes, has significant negative impact on function among people with progressive forms of MS. However, there is variablity of information regarding the impact of pain associated with lower limb spasticity on functionality and quality of life among individuals with diagnosed progressive forms of MS.
Objectives and aims: To correlate the impact of pain and lower limb spasticity to functionality and quality of life in patients with progressive forms of MS.
Methods: Cross-sectional analysis of data from 85 patients with diagnosed primary and secondary progressive MS, The Expanded Disability Status Scale (EDSS) score 2-6.5 and lower limb spasticity were conducted. Patients were reffered to inpatient rehabilitation at Clinic for rehabilitation Dr Miroslav Zotovic in Belgrade. The Modified Ashwort Scale (MAS) was used for the spasticity estimation. The Timed 25 Foot walk (T25FW) was used to quantify the mobility and function of the leg. For correlate functional activity according to pain intensity self-assesment scales: The Multiple Sclerosis Spasticity Scale 88 (MSSS-88) with its subscale Pain and discomfort (PD) and Physical Health Composite Score (PHC) as a part of the Multiple Sclerosis Quality of Life-54 (MSQoL-54) in comparation with Pain domen of the same scale were used.
Results: A statistically significant correlation was found between EDSS and T25 W (rs=0,651; p< 0,001), MAS and EDSS (rs=0,413; p< 0,001), PD subscale and MSSS-88 (r=0,918; p< 0,001), Pain and PHC (r=0,819; p< 0,001). The associations between pain intensity and measures of function are consistent with the literature on the MS population at large.
Conclusions: The results suggest that pain becomes worse in individuals with higher disability score and spasticity level has negative impact on functionality and quality of life.
Disclosure: Nothing to disclose

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